68
Therapeutic Cloning
question is closely bound up with the principle of division of
labor the first multicellular organism was probably a cluster
of similar cells, but these units soon lost their original homo-
geneity: the single cluster would come to be divided into two
groups of cells, which may be called somatic and reproductive.
As the complexity of the metazoan body increased, these two
groups became more sharply separated from each other. Very
soon the somatic cells surpassed the reproductive in number,
and during this increase they became more and more broken
up by the division of labor into sharply separated systems of
tissues. As these changes took place, the power of reproduc-
ing large parts of the organism was lost, while the power of
reproducing the whole individual became concentrated in the
reproductive cells alone. But, it does not therefore follow that
the somatic cells were compelled to lose the power of unlim-
ited cell reproduction.
So, Weismann made the astonishing prediction that while
the germ-line cells of multicellular animals, such as humans,
were immortal (specifically, they could replicate without
limit), the somatic cells were in fact mortal that is, they had
the capacity to divide only a finite number of divisions:
Death takes place because a worn-out tissue cannot for-
ever renew itself, and because a capacity for increase by
means of cell-division is not everlasting, but finite. [2]
HAYFLICKS EXPERIMENT
In 1961, the cell biologist Leonard Hayflick published the
seminal work that convinced the scientific community that
cells in the human body the somatic cells are mortal. [3]
They could divide and proliferate, but as Weismann had
predicted so many years earlier, even with optimum growth